Brexit critic and member of European Parliament Nigel Farage will not stand as candidate for General election 2019 on 12 December.
“I don’t want to be in politics for the rest of my life,” he said.
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Mr Farage, who has stood unsuccessfully for Parliament seven times, also criticised the PM’s Brexit deal.
Mr Farage had called on the prime minister to drop his Brexit deal, unite in a “Leave alliance” or face a Brexit Party candidate in every seat in the election.
He told the Marr show: “I always thought that to win an election, get a big majority so we can get a proper Brexit, a coming-together would be the objective.
“I still hope and pray it happens but it doesn’t look like it will.”
Mr Johnson maintains that the only way out of the EU is to “go with the deal we’ve got”.
The prime minister told Sophy Ridge on Sky that he was “deeply, deeply disappointed” to miss the 31 October deadline to secure Brexit, calling it “a matter of deep regret”.
The PM had previously said he would rather “die in a ditch” than ask the EU to delay Brexit beyond Halloween.
Mr Johnson told the programme that he was sorry, and took responsibility, for missing the date, but accused Parliament of failing to implement his deal.
Mr Farage said Mr Johnson’s deal “kills off any chance of genuine independence”.
“If Boris is determined to stick to this new EU treaty, then that is not Brexit,” he said
Brexit critic Nigel Farage will not stand for MP in general election.